Literature summary for 6.1.1.5 extracted from

Jenal.U.; Rechsteiner, T.; Tan, P.Y.; Buhlmann, E.; Meile, L.; Leisinger, T.
Isoleucyl-tRNA synthetase of Methanobacterium thermoautotrophicum Marburg. Cloning of the gene, nucleotide sequence, and localization of a base change conferring resistance to pseudomonic acid (1991), J. Biol. Chem., 266, 10570-10577.

Search for more literature for 6.1.1.5

Cloned(Commentary)

Cloned (Comment)	Organism
-	Methanothermobacter thermautotrophicus

Protein Variants

Protein Variants	Comment	Organism
G590D	pseudomonic-acid resistant mutant MBT10, with a Gly590 to aspartic acid transition	Methanothermobacter thermautotrophicus

Inhibitors

Inhibitors	Comment	Organism	Structure
pseudomonic acid	-	Methanothermobacter thermautotrophicus

Organism

Organism	UniProt	Comment	Textmining
Methanothermobacter thermautotrophicus	-	-	-
Methanothermobacter thermautotrophicus	-	wild-type end pseudomonic-acid resistant mutant MBT10, with a Gly590 to aspartic acid transition	-
Methanothermobacter thermautotrophicus Marburg / DSM 2133	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-isoleucine + tRNAIle	-	Methanothermobacter thermautotrophicus	AMP + diphosphate + L-isoleucyl-tRNAIle	-	?
ATP + L-isoleucine + tRNAIle	-	Methanothermobacter thermautotrophicus Marburg / DSM 2133	AMP + diphosphate + L-isoleucyl-tRNAIle	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)