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Literature summary for 6.1.1.4 extracted from

  • Lin, C.S.; Irwin, R.; Chirikjian, J.G.
    Kinetic studies of leucyl transfer RNA synthetase from bakers' yeast. Order of addition of substrates and release of products (1975), J. Biol. Chem., 250, 9299-9303.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
AMP
-
Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0001
-
tRNALeu
-
Saccharomyces cerevisiae
0.01
-
Leu
-
Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + L-leucine + tRNALeu = AMP + diphosphate + L-leucyl-tRNALeu bi uni uni bi ping-pong mechanism with ordered addition of ATP and leucine and random release of AMP and leucyl-tRNALeu Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-leucine + tRNALeu
-
Saccharomyces cerevisiae AMP + diphosphate + L-leucyl-tRNALeu
-
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