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Literature summary for 6.1.1.3 extracted from

  • Freist, W.; Gauss, D.H.
    Threonyl-tRNA synthetase. (1995), Biol. Chem. Hoppe-Seyler, 376, 213-224.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
borrelidin
-
Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Bos taurus 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Aesculus hippocastanum
Mg2+ required Saccharomyces pastorianus
Mg2+ required Mus musculus
Mg2+ required Thermus thermophilus
Mg2+ required Escherichia coli
Mg2+ required Homo sapiens
Mg2+ required Rattus norvegicus
Mg2+ required Saccharomyces cerevisiae
Mg2+ required Bos taurus
Mg2+ required Oryctolagus cuniculus
Mg2+ required Geobacillus stearothermophilus
Mg2+ Mg2+ can be substituted by Ba2+, Ca2+, Mn2+ and Co2+ Rattus norvegicus
Mg2+ Mg2+ can be substituted by Ca2+ and Mn2+. Zn2+ and Ni2+ can only very poorly replace Mg2+ Escherichia coli
Zn2+ enzyme contains 1 Zn2+ per subunit Escherichia coli

Organism

Organism UniProt Comment Textmining
Aesculus hippocastanum
-
-
-
Bos taurus
-
-
-
Escherichia coli
-
-
-
Geobacillus stearothermophilus
-
-
-
Homo sapiens
-
-
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-
Saccharomyces pastorianus
-
-
-
Thermus thermophilus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Ehrlich ascites carcinoma cell
-
Mus musculus
-
liver
-
Mus musculus
-
liver
-
Rattus norvegicus
-
liver
-
Bos taurus
-
placenta
-
Homo sapiens
-
reticulocyte
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-threonine + tRNAThr
-
Aesculus hippocastanum AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Saccharomyces pastorianus AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Mus musculus AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Thermus thermophilus AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Escherichia coli AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Homo sapiens AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Rattus norvegicus AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Saccharomyces cerevisiae AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Bos taurus AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Oryctolagus cuniculus AMP + diphosphate + L-threonyl-tRNAThr
-
?
ATP + L-threonine + tRNAThr
-
Geobacillus stearothermophilus AMP + diphosphate + L-threonyl-tRNAThr
-
?