Crystallization (Comment) | Organism |
---|---|
AsnRS with bound asparaginyladenylate, AsnAMP, X-ray diffraction structure anaylsis at 2.6 A resolution | Thermus thermophilus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | binding kinetics, affinities, and thermidynamics, molecular dynamics simulations, overview | Thermus thermophilus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | a single Mg2+ bound to ATP alpha-phosphate | Thermus thermophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-asparagine + tRNAAsn | calculations of substrate binding and reaction mechanism, overview | Thermus thermophilus | AMP + diphosphate + L-asparaginyl-tRNAAsn | - |
? | |
additional information | analysis of the molecular mechanism by molecular dynamics simulations and computational calculations using wild-type andmutant enzymes, overview | Thermus thermophilus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AsnRS | - |
Thermus thermophilus |
Asparaginyl-tRNA synthetase | - |
Thermus thermophilus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | a single Mg2+ bound to the ligand's alpha-phosphate | Thermus thermophilus |