Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-histidine + tRNAHis | Homo sapiens | - |
AMP + diphosphate + L-histidyl-tRNAHis | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-histidine + tRNAHis | - |
Homo sapiens | AMP + diphosphate + L-histidyl-tRNAHis | - |
? |
Synonyms | Comment | Organism |
---|---|---|
histidyl-transfer RNA synthetase | - |
Homo sapiens |
Histidyl-tRNA synthetase | - |
Homo sapiens |
HRS | - |
Homo sapiens |
Jo-1 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme induces muscle inflammation in B6.TLR2 and B6.TLR4 knockout mice. The enzyme induces interleukin 8 production in toll-like-receptor-transfected HEK-293 cells | Homo sapiens |