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Literature summary for 6.1.1.21 extracted from

  • Boguslawski, G.; Vodkin, M.H.; Finkelstein, D.B.; Fink, G.R.
    Histidyl-tRNAs and histidyl-tRNA synthetases in wild type and cytoplasmic petite mutants of Saccharomyces cerevisiae (1974), Biochemistry, 13, 4659-4667.
    View publication on PubMed
Search for more literature for 6.1.1.21

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0006
-
 His peptite mutant EB2 mitochondrial enzyme Saccharomyces cerevisiae
0.0009
-
 His wild-type mitochondrial enzyme Saccharomyces cerevisiae
0.001
-
 His petite mutant EB2 cytoplasmic enzyme Saccharomyces cerevisiae
0.0018
-
 His wild-type cytoplasmic enzyme Saccharomyces cerevisiae
0.08
-
 His wild-type mitochondrial enzyme Saccharomyces cerevisiae
0.14
-
 ATP ATP, , wild-type cytoplasmic enzyme Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Saccharomyces cerevisiae 5737
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 wild-type S288C and cytoplasmic petite mutant EB2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-histidine + tRNAHis the cytoplasmic enzyme efficiently charges bulk E. coli tRNA, the mitochondrial enzyme does not charge it Saccharomyces cerevisiae AMP + diphosphate + L-histidyl-tRNAHis
-
 ?