Crystallization (Comment) | Organism |
---|---|
crystal structure of enzyme-substrate complex with histidyl-tRNA synthetase, ATP, and the amino acid analog histidinyl | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
R259H | mutant Arg259His, with 1000fold decreased second order rate constant kcat/Km for the ATP-diphosphate exchange, and 500fold decreased kcat/Km for aminoacylation | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
wild-type and mutant Arg259His | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-histidine + tRNAHis | - |
Escherichia coli | AMP + diphosphate + L-histidyl-tRNAHis | - |
? |