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Literature summary for 6.1.1.20 extracted from

  • Plateau, P.; Mayaux, J.F.; Blanquet, S.
    Zinc(II)-dependent synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate by Escherichia coli and yeast phenylalanyl transfer ribonucleic acid synthetases (1981), Biochemistry, 20, 4654-4662.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Zn2+ inhibition of tRNAPhe aminoacylation, required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Escherichia coli
Zn2+ inhibition of tRNAPhe aminoacylation, required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Escherichia coli
Zn2+ required for conversion of ATP into diadenosine 5',5'''-P1,P4-tetraphosphate Saccharomyces cerevisiae
Zn2+ inhibition of tRNAPhe aminoacylation Escherichia coli
Zn2+ inhibition of tRNAPhe aminoacylation Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-phenylalanine + tRNAPhe
-
Escherichia coli AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?
ATP + L-phenylalanine + tRNAPhe
-
Saccharomyces cerevisiae AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?
additional information synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate Escherichia coli ?
-
?
additional information synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate Saccharomyces cerevisiae ?
-
?