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Literature summary for 6.1.1.19 extracted from
- Analysis of the kinetic mechanism of arginyl-tRNA synthetase (2006), Biochim. Biophys. Acta, 1764, 307-319.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| K2SO4 | 45 mM | Escherichia coli |  |
| KCl | - |
Escherichia coli | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| K+ | 50 mM is required for full activity | Escherichia coli | |
| Mg2+ | dependent | Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Escherichia coli MRE 600 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DEAE-Sepharose CL-6B column chromatography, hydroxylapatite chromatography, Sepharose CL-2B column chromatography, and Sephacryl S-300 gel filtration | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-arginine + tRNAArg | - |
Escherichia coli | AMP + diphosphate + L-arginyl-tRNAArg | - |
? | |
| ATP + L-arginine + tRNAArg | - |
Escherichia coli MRE 600 | AMP + diphosphate + L-arginyl-tRNAArg | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| arginyltRNA synthetase | - |
Escherichia coli |
| ArgRS | - |
Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Escherichia coli | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 160 | - |
- |
Escherichia coli | KCl | |
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