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Literature summary for 6.1.1.12 extracted from
- Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis (2013), Clin. Vaccine Immunol., 20, 276-281.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Brugia malayi |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Brugia malayi | 5737 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-aspartate + tRNAAsp | Brugia malayi | - |
AMP + diphosphate + L-aspartyl-tRNAAsp | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Brugia malayi | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| magnesium sulfate precipitation, column chromatography, nickel affinity chromatography, and anion-exchange chromatography | Brugia malayi |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-aspartate + tRNAAsp | - |
Brugia malayi | AMP + diphosphate + L-aspartyl-tRNAAsp | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AsnRS | - |
Brugia malayi |
| Aspartyl-tRNA synthetase | - |
Brugia malayi |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Brugia malayi | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme induces an anti-inflammatory effect in mice with T-cell transfer colitis by interacting with interleukin-8 receptors | Brugia malayi |
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Release 2023.1 (January 2023)
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