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Literature summary for 6.1.1.12 extracted from

  • Choi, H.; Gabriel, K.; Schneider, J.; Otten, S.; McClain, W.H.
    Recognition of acceptor-stem structure of tRNA(Asp) by Escherichia coli aspartyl-tRNA synthetase (2003), RNA, 9, 386-393.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.12

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-aspartate + tRNAAsp Escherichia coli protein-RNA recognition between the enzyme and tRNA is highly specific and essential for cell viability AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp protein-RNA recognition mechanism, backbone interactions are an important functional component of the tRNA synthetase interaction Escherichia coli
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-aspartate + tRNAAsp wild-type Escherichia coli tRNAAsp and some recombinant acceptor stem mutants from Saccharomyces cerevisiae, overview Escherichia coli AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp protein-RNA recognition between the enzyme and tRNA is highly specific and essential for cell viability Escherichia coli AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
additional information no activity with wild-type tRNAAsp and several acceptor stem mutants from Saccharomyces cerevisiae, overview Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
Aspartic acid translase
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 Escherichia coli
Aspartyl ribonucleate synthetase
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 Escherichia coli
aspartyl ribonuleic synthetase
-
 Escherichia coli
Aspartyl-transfer ribonucleic acid synthetase
-
 Escherichia coli
Aspartyl-transfer RNA synthetase
-
 Escherichia coli
Aspartyl-tRNA synthetase
-
 Escherichia coli