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Literature summary for 6.1.1.11 extracted from

  • Weygand-Durasevic, I.; Ban, N.; Jahn, D.; Söll, D.
    Yeast seryl-tRNA synthetase expressed in Escherichia coli recognizes bacterial serine-specific tRNAs in vivo (1993), Eur. J. Biochem., 214, 869-877.
    View publication on PubMed
Search for more literature for 6.1.1.11

Inhibitors

Inhibitors Comment Organism Structure
DL-Serine hydroxamate inhibition constant for Saccharomyces cerevisiae enzyme is 90fold higher than for Escherichia coli enzyme Escherichia coli
DL-Serine hydroxamate inhibition constant for Saccharomyces cerevisiae enzyme is 90fold higher than for Escherichia coli enzyme Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
53000
-
 x * 53000, SDS-PAGE Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 temperature-sensitive mutant
-
Saccharomyces cerevisiae
-
 overexpression in Escherichia coli
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.015
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-serine + tRNASer
-
 Escherichia coli AMP + diphosphate + L-seryl-tRNASer
-
 ?
ATP + L-serine + tRNASer enzyme aminoacylates E. coli tRNA with Ser much more poorly than its homologous tRNAs Saccharomyces cerevisiae AMP + diphosphate + L-seryl-tRNASer
-
 ?

Subunits

Subunits Comment Organism
? x * 53000, SDS-PAGE Saccharomyces cerevisiae