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Literature summary for 6.1.1.11 extracted from

  • Herzog, W.; Mueller, K.; Huisken, J.; Stainier, D.Y.
    Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development (2009), Circ. Res., 104, 1260-1266.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
siRNA
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-serine + tRNASer Homo sapiens
-
AMP + diphosphate + L-seryl-tRNASer
-
?
ATP + L-serine + tRNASer Danio rerio
-
AMP + diphosphate + L-seryl-tRNASer
-
?

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Danio rerio
-
HUVEC cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-serine + tRNASer
-
Homo sapiens AMP + diphosphate + L-seryl-tRNASer
-
?
ATP + L-serine + tRNASer
-
Danio rerio AMP + diphosphate + L-seryl-tRNASer
-
?

Synonyms

Synonyms Comment Organism
Seryl-tRNA synthetase
-
Homo sapiens
Seryl-tRNA synthetase
-
Danio rerio

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens
ATP
-
Danio rerio

General Information

General Information Comment Organism
physiological function seryl-tRNA synthetase possesses an angiogenesis-regulating capacity Homo sapiens
physiological function seryl-tRNA synthetase possesses an angiogenesis-regulating capacity Danio rerio