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Literature summary for 6.1.1.1 extracted from
- One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetases (2009), Bioorg. Med. Chem. Lett., 19, 3845-3847.
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | a rapid, straightforward, one plasmid dual positive/negative selection system for the evolution of aminoacyl-tRNA synthetases with altered specifities in Escherichia coli is developed | Methanocaldococcus jannaschii |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-tyrosine + tRNATyr | Methanocaldococcus jannaschii | - |
AMP + diphosphate + L-tyrosyl-tRNATyr | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanocaldococcus jannaschii | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-tyrosine + tRNATyr | - |
Methanocaldococcus jannaschii | AMP + diphosphate + L-tyrosyl-tRNATyr | - |
? | |
| ATP + p-iodophenylalanine + tRNATyr | a variant of the Methanococcus jannaschii tyrosyl synthetase that selectively incorporates para-iodophenylalanine in response to an amber stop codon is identified | Methanocaldococcus jannaschii | AMP + diphosphate + p-iodophenylalanyl-tRNATyr | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| tRNATyr/tyrosyl-tRNA synthetase | - |
Methanocaldococcus jannaschii |
| tyrosyl synthetase | - |
Methanocaldococcus jannaschii |
| Tyrosyl-tRNA synthetase | - |
Methanocaldococcus jannaschii |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Methanocaldococcus jannaschii | |
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Release 2023.1 (January 2023)
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