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Literature summary for 5.6.2.1 extracted from

  • Wu, G.; Qi, X.; Mo, X.; Yu, G.; Wang, Q.; Zhu, T.; Gu, Q.; Liu, M.; Li, J.; Li, D.
    Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus (2018), Eur. J. Med. Chem., 148, 268-278 .
    View publication on PubMed
Search for more literature for 5.6.2.1

Inhibitors

Inhibitors Comment Organism Structure
versixanthone G
-
 Homo sapiens
versixanthone H
-
 Homo sapiens
versixanthone I
-
 Homo sapiens
versixanthone J
-
 Homo sapiens
versixanthone K
-
 Homo sapiens
versixanthone L
-
 Homo sapiens
versixanthone M
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
H-1975 cell
-
 Homo sapiens
-
HCT-116 cell
-
 Homo sapiens
-
HEK-293 cell
-
 Homo sapiens
-
HL-60 cell
-
 Homo sapiens
-
HO-8910 cell
-
 Homo sapiens
-
K-562 cell
-
 Homo sapiens
-
MGC-803 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
supercoiled plasmid pBR322 DNA
-
 Homo sapiens relaxed plasmid pBR322 DNA
-
 ?

Synonyms

Synonyms Comment Organism
DNA topoisomerase I
-
 Homo sapiens
Topo I
-
 Homo sapiens