Literature summary for 5.6.1.3 extracted from

Kinoshita, K.; Noetzel, T.L.; Arnal, I.; Drechsel, D.N.; Hyman, A.A.
Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1 (2006), J. Muscle Res. Cell Motil., 27, 107-114.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	Xenopus sp.	kinesin MCAK/XKCM1destabilizes microtubules. Kinesin MCAK/XKCM1 is essential for controlling the distribution of microtubules by inducing their depolymerization	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Organism

Organism	UniProt	Comment	Textmining
Xenopus sp.	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + a kinesin associated with a microtubule at position n	kinesin MCAK/XKCM1destabilizes microtubules. Kinesin MCAK/XKCM1 is essential for controlling the distribution of microtubules by inducing their depolymerization	Xenopus sp.	ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)	-	?

Synonyms

Synonyms	Comment	Organism
kinesin MCAK/XKCM1	-	Xenopus sp.

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Release 2023.1 (January 2023)