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Literature summary for 5.5.1.12 extracted from

  • Peters, R.J.; Ravn, M.M.; Coates, R.M.; Croteau, R.B.
    Bifunctional abietadiene synthase: Free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites (2001), J. Am. Chem. Soc., 123, 8974-8978.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Abies grandis

Protein Variants

Protein Variants Comment Organism
D404A unreactive with geranylgeranyl diphosphate Abies grandis
D621A unreactive with (+)-copalyl diphosphate Abies grandis

Inhibitors

Inhibitors Comment Organism Structure
14,15-dihydro-15-azageranylgeranyl diphosphate
-
Abies grandis
geranylgeranyl diphosphate
-
Abies grandis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
geranylgeranyl diphosphate
-
Abies grandis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
gel filtration Abies grandis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranylgeranyl diphosphate Abies grandis
-
(+)-copalyl diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Abies grandis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate
-
Abies grandis (+)-copalyl diphosphate
-
?

Subunits

Subunits Comment Organism
monomer
-
Abies grandis

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.2
-
geranylgeranyl diphosphate
-
Abies grandis