Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.4.99.9 extracted from

  • Errey, J.C.; Mann, M.C.; Fairhurst, S.A.; Hill, L.; McNeil, M.R.; Naismith, J.H.; Percy, J.M.; Whitfield, C.; Field, R.A.
    Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: Fluorinated substrates, kinetics and equilibria (2009), Org. Biomol. Chem., 7, 1009-1016.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Klebsiella pneumoniae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
UDP-D-galactofuranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
0.2
-
UDP-6-deoxy-6-fluoro-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
0.203
-
UDP-2-deoxy-2-fluoro-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
0.28
-
UDP-3-deoxy-3-fluoro-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
0.805
-
UDP-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
1.14
-
UDP-2-amino-2-deoxy-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
3.15
-
UDP-6-deoxy-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity with UDP-6-deoxy-Dgalactopyranose, UDP-2-azido-2-deoxy-D-galactopyranose, and UDP-2-acetamido-2-deoxy-D-galactopyranose Klebsiella pneumoniae ?
-
?
UDP-2-amino-2-deoxy-D-galactopyranose
-
Klebsiella pneumoniae ?
-
?
UDP-2-deoxy-2-fluoro-D-galactopyranose
-
Klebsiella pneumoniae ?
-
?
UDP-3-deoxy-3-fluoro-D-galactopyranose
-
Klebsiella pneumoniae ?
-
?
UDP-6-deoxy-6-fluoro-D-galactopyranose
-
Klebsiella pneumoniae ?
-
?
UDP-6-deoxy-D-galactopyranose
-
Klebsiella pneumoniae ?
-
?
UDP-D-galactopyranose
-
Klebsiella pneumoniae UDP-D-galactofuranose
-
?

Synonyms

Synonyms Comment Organism
UDP-D-galactopyranose mutase
-
Klebsiella pneumoniae
UGM
-
Klebsiella pneumoniae

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0007
-
UDP-2-deoxy-2-fluoro-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
0.9
-
UDP-3-deoxy-3-fluoro-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
1.4
-
UDP-2-amino-2-deoxy-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
3.5
-
UDP-6-deoxy-6-fluoro-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
35.3
-
UDP-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
36.8
-
UDP-D-galactofuranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae
42.2
-
UDP-6-deoxy-D-galactopyranose in 50 mM MOPS, 10 mM sodium dithionite, 2 mM MgCl2 pH 7.4, at 37°C Klebsiella pneumoniae

Cofactor

Cofactor Comment Organism Structure
FAD
-
Klebsiella pneumoniae