Cloned (Comment) | Organism |
---|---|
functional recombinant enzyme expression in Saccharomyces cerevisiae strain GIL77, coexpression with alpha-onocerin synthase leading to the production of tohogenol and serratenediol, NMR metabolite identification, overview | Lycopodium clavatum |
Protein Variants | Comment | Organism |
---|---|---|
additional information | while the heterologous LCC gene expression produces the bicyclic triterpene pre-alpha-onocerin, a combination of LCC and alpha-onocerin synthase LCD produces onoceranes, and that of LCC and tohogenol synthase LCE produces serratanes | Lycopodium clavatum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene | Lycopodium clavatum | - |
pre-alpha-onocerin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lycopodium clavatum | A0A125SXN1 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(3S,22S)-2,3:22,23-diepoxy-2,3,22,23-tetrahydrosqualene | - |
Lycopodium clavatum | pre-alpha-onocerin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Lcc | - |
Lycopodium clavatum |
General Information | Comment | Organism |
---|---|---|
metabolism | ferns are known to produce onoceroids including onoceranes and serratanes having unusual structures among triterpenes. Serratanes are directly biosynthesized from pre-alpha-onocerin, synthesized by pre-alpha-onocerin synthase, and not from alpha-onocerin, synthesized by alpha-onocerin synthase, EC 5.4.99.66, from pre-alpha-onocerin | Lycopodium clavatum |
physiological function | ferns are known to produce onoceroids including onoceranes and serratanes having unusual structures among triterpenes. Serratanes are directly biosynthesized from pre-alpha-onocerin, synthesized by pre-alpha-onocerin synthase, and not from alpha-onocerin, synthesized by alpha-onocerin synthase, EC 5.4.99.66, from pre-alpha-onocerin | Lycopodium clavatum |