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Literature summary for 5.4.99.63 extracted from

  • Jung, W.S.; Kim, E.; Yoo, Y.J.; Ban, Y.H.; Kim, E.J.; Yoon, Y.J.
    Characterization and engineering of the ethylmalonyl-CoA pathway towards the improved heterologous production of polyketides in Streptomyces venezuelae (2014), Appl. Microbiol. Biotechnol., 98, 3701-3713.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Streptomyces venezuelae
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-
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Synonyms

Synonyms Comment Organism
ethylmalonyl-CoA mutase
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Streptomyces venezuelae
meaA
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Streptomyces venezuelae

Cofactor

Cofactor Comment Organism Structure
vitamin B12
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Streptomyces venezuelae

General Information

General Information Comment Organism
malfunction intracellular ethylmalonyl-CoA concentration is increase by the deletion of the meaA gene encoding coenzyme B12-dependent ethylmalonyl-CoA mutase in combination with ethylmalonate supplementation Streptomyces venezuelae