Cloned (Comment) | Organism |
---|---|
- |
Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
Q450H | nonviable single mutant produces minor amount achilleol A as the sole product | Saccharomyces cerevisiae |
Q450H/V454I | mutant produces lanosterol, (13alphaH)-isomalabarica-14(26),17E,21-trien-3 beta-ol, protosta-16,24-dien-3beta-ol in a ratio of 75:16:9 | Saccharomyces cerevisiae |
T384Y | mutant produces lanosterol, parkeol, 9beta-lanosta-7,24-dien-3 beta-ol, protosta-13(17),24-dien-3beta-ol and protosta-16,24-dien-3beta-ol in the ratio of 63:31.5:3.5:1:1 without compounds achilleol A and (13alphaH)-isomalabarica-14(26),17E,21-trien-3 beta-ol | Saccharomyces cerevisiae |
T384Y/Q450H | mutant produces lanosterol, parkeol, 9 beta -lanosta-7,24-dien-3 beta-ol in a ratio of 1:98:1 | Saccharomyces cerevisiae |
T384Y/Q450H/V454I | mutant generates parkeol as the sole product, Vmax/Km 18fold decreased for 3S-2,3-oxidosqualene compared to wild-type | Saccharomyces cerevisiae |
T384Y/V454I | mutant produces lanosterol, parkeol, 9 beta -lanosta-7,24-dien-3 beta-ol in a ratio of 10:84:6 | Saccharomyces cerevisiae |
V454I | mutant produces poor amounts of lanosterol and (13alphaH)-isomalabarica-14(26),17E,21-trien-3 beta-ol (ratio 90:10) | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
ERG7 | - |
Saccharomyces cerevisiae |
Oxidosqualene-lanosterol cyclase | - |
Saccharomyces cerevisiae |