Any feedback?
Literature summary for 5.4.99.47 extracted from
- Directed evolution to investigate steric control of enzymatic oxidosqualene cyclization. An isoleucine-to-valine mutation in cycloartenol synthase allows lanosterol and parkeol biosynthesis (1999), J. Am. Chem. Soc., 121, 9887-9888.
No PubMed abstract available
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (3S)-2,3-oxidosqualene | - |
Saccharomyces cerevisiae | cycloartenol + lanosterol + parkeol | the cycloartenol synthase 1 mutant I481V makes a relative product ratio of 52:26:22 | ? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CAS1Ile481Val | - |
Saccharomyces cerevisiae |
| cycloartenol synthase 1 mutant I481V | cf. EC 5.4.99.8 | Saccharomyces cerevisiae |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
