Cloned (Comment) | Organism |
---|---|
- |
Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | efficient and rapid targeting of Pus2p in yeast mitochondria | Saccharomyces cerevisiae | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
mitochondrial tRNAArg(UCU) uridine27 | Saccharomyces cerevisiae | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | mitochondrial tRNAArg(UCU) pseudouridine27 | - |
? | |
mitochondrial tRNAArg(UCU) uridine27 | Saccharomyces cerevisiae BY4742 | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | mitochondrial tRNAArg(UCU) pseudouridine27 | - |
? | |
mitochondrial tRNALys(UUU) uridine28 | Saccharomyces cerevisiae | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | mitochondrial tRNALys(UUU) pseudouridine28 | - |
? | |
mitochondrial tRNALys(UUU) uridine28 | Saccharomyces cerevisiae BY4742 | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | mitochondrial tRNALys(UUU) pseudouridine28 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P53167 | - |
- |
Saccharomyces cerevisiae BY4742 | P53167 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
mitochondrial tRNAArg(UCU) uridine27 | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | Saccharomyces cerevisiae | mitochondrial tRNAArg(UCU) pseudouridine27 | - |
? | |
mitochondrial tRNAArg(UCU) uridine27 | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | Saccharomyces cerevisiae BY4742 | mitochondrial tRNAArg(UCU) pseudouridine27 | - |
? | |
mitochondrial tRNALys(UUU) uridine28 | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | Saccharomyces cerevisiae | mitochondrial tRNALys(UUU) pseudouridine28 | - |
? | |
mitochondrial tRNALys(UUU) uridine28 | Pus2p is specifically dedicated to mitochondrial tRNA modification, the corresponding modification in cytoplasmic tRNAs is catalyzed by another protein (Pus1p). Pus2p does not catalyze pseudouridylation at position 72. Other pseudouridines in cytoplasmic yeast tRNA normally formed by Pus1p (positions 1, 34, 36, 65, 67) are absent in the mitochondrial compartment | Saccharomyces cerevisiae BY4742 | mitochondrial tRNALys(UUU) pseudouridine28 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mitochondrial-specific tRNA:Psi-synthase | - |
Saccharomyces cerevisiae |
Pus2 protein | - |
Saccharomyces cerevisiae |
Pus2p | - |
Saccharomyces cerevisiae |
tRNA:PSI27/28-synthase | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
malfunction | disruption of the PUS2 gene leads to the absence of pseudouridine27 residues in the mitochondrial tRNAArg(UCU) and pseudouridine28 in the mitochondrial tRNALys(UUU) | Saccharomyces cerevisiae |