Literature summary for 5.4.99.41 extracted from

Shan, H.; Segura, M.J.; Wilson, W.K.; Lodeiro, S.; Matsuda, S.P.
Enzymatic cyclization of dioxidosqualene to heterocyclic triterpenes (2005), J. Am. Chem. Soc., 127, 18008-18009.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Saccharomyces cerevisiae lacking lanosterol and ergosterol synthase activities	Arabidopsis thaliana

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	-	isoform LUP1	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(3S,22S)-2,3:22,23-dioxidosqualene	-	Arabidopsis thaliana	(2R,4aR,6aS,6bS,10R,12aS,14aR,14bS)-2-(1-hydroxy-1-methylethyl)-4a,6a,6b,9,9,12a-hexamethylicosahydro-2H-phenanthro[1,2-h]chromen-10-ol + (3alpha,5xi,8alpha,9xi,10alpha,13aalpha,14beta,17xi,20R,24R)-20,24-epoxydammarane-3,25-diol + (3alpha,5xi,8alpha,9xi,10alpha,13alpha,14beta,17xi,24R)-20,24-epoxydammarane-3,25-diol	products 5_4_99.B3_11.8, 5_4_99.B3_11.9a and 5_4_99.B3_11.9b in ratio 3:4:2, almost complete consumption of substrate	?

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Release 2023.1 (January 2023)