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Literature summary for 5.4.3.8 extracted from

  • Pugh, C.E.; Harwood, J.L.; John, R.A.
    Mechanism of glutamate semialdehyde aminotransferase roles of diamino- and dioxo-intermediates in the synthesis of aminolevulinate (1992), J. Biol. Chem., 267, 1584-1588.
    View publication on PubMed
Search for more literature for 5.4.3.8

Organism

Organism UniProt Comment Textmining
Pisum sativum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pisum sativum

Reaction

Reaction Comment Organism Reaction ID
L-glutamate 1-semialdehyde = 5-aminolevulinate the catalytic mechanism includes enzyme-bound diaminovalerate as a central intermediate Pisum sativum
a

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Pisum sativum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-4-Amino-5-oxopentanoate
-
 Pisum sativum 5-Amino-4-oxopentanoate
-
 ?
4,5-Diaminovalerate is a substrate for the pyridoxal 5'-phosphate form of the enzyme Pisum sativum ?
-
 ?
4,5-Dioxovalerate is a substrate for the pyridoxamine form of the enzyme Pisum sativum 5-Amino-4-oxopentanoate
-
 ?

Cofactor

Cofactor Comment Organism Structure
pyridoxamine 5'-phosphate only the pyridoxamine form of the enzyme is active Pisum sativum