Literature summary for 5.4.3.6 extracted from

Christianson, C.V.; Montavon, T.J.; Van Lanen, S.G.; Shen, B.; Bruner, S.D.
The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway (2007), Biochemistry, 46, 7205-7214.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli with His-tag	Streptomyces globisporus

Crystallization (Commentary)

Crystallization (Comment)	Organism
refined to 2.5 A resolution. Enzyme has a closed active site well suited to retain ammonia and minimize the formation of lyase elimination products	Streptomyces globisporus

Organism

Organism	UniProt	Comment	Textmining
Streptomyces globisporus	-	-	-

Subunits

Subunits	Comment	Organism
tetramer	crystallization data	Streptomyces globisporus

Cofactor

Cofactor	Comment	Organism	Structure
methylideneimidazole-5-one	Mio cofactor, formed by the self-condensation of Ala152, Ser153, and Gly154	Streptomyces globisporus

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Release 2023.1 (January 2023)