Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells and HEK-293T cells | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
IMP | IMP stimulates by more than 100fold the intrinsic glucose-1,6-bisphosphatase activity of recombinant PMM1 while inhibiting its phosphoglucomutase activity | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-D-glucose 1,6-bisphosphate | - |
Mus musculus | ? | - |
? | |
alpha-D-mannose 1-phosphate | - |
Mus musculus | alpha-D-mannose 6-phosphate | - |
? | |
additional information | PMM1 is less specific: it has nearly equal phosphomannomutase and phosphoglucomutase activities as well as a modest glucose-1,6-bisphosphatase activity corresponding to about 3% of its phosphomannomutase activity | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IMP-sensitive glucose-1,6-bisphosphatase | - |
Mus musculus |
phosphomannomutase 1 | - |
Mus musculus |
PMM1 | multifunctional enzyme | Mus musculus |