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Literature summary for 5.4.2.8 extracted from

  • Kedzierski, L.; Malby, R.L.; Smith, B.J.; Perugini, M.A.; Hodder, A.N.; Ilg, T.; Colman, P.M.; Handman, E.
    Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms (2006), J. Mol. Biol., 363, 215-227.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Leishmania mexicana
expression in Leishmania mexicana does not restore virulence of an enzyme deletion mutant Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
free enzyme and in complex with glucose 1,6-bisphosphate at 2.1 and 2.9 A resolution, resp. Comparison with structure of human enzyme Leishmania mexicana

Protein Variants

Protein Variants Comment Organism
additional information enzyme knock-out mutant is avirulent Leishmania mexicana
additional information expression in Leishmania mexicana does not restore virulence of an enzyme deletion mutant Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
31100
-
x * 31100, SDS-PAGE Homo sapiens
31100
-
x * 31100, SDS-PAGE Leishmania mexicana

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Leishmania mexicana Q95ZD7
-
-

Subunits

Subunits Comment Organism
? x * 31100, SDS-PAGE Homo sapiens
? x * 31100, SDS-PAGE Leishmania mexicana