Literature summary for 5.4.2.10 extracted from

Tavares, I.M.; Jolly, L.; Pompeo, F.; Leitao, J.H.; Fialho, A.M.; Sa-Correia, I.; Mengin-Lecreulx, D.
Identification of the Pseudomonas aeruginosa glmM gene, encoding phosphoglucosamine mutase (2000), J. Bacteriol., 182, 4453-4457.

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Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in Escherichia coli	Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-glucoamine 6-phosphate	Pseudomonas aeruginosa	involved in formation of cell-wall precursor UDP-N-acetylglucosamine	D-glucosamine 1-phosphate	-	r

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
near homogeneity, recombinant enzyme	Pseudomonas aeruginosa

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.06	-	substrate: D-glucose 1-phosphate	Pseudomonas aeruginosa
0.55	-	substrate: D-mannose 1-phosphate	Pseudomonas aeruginosa
2.5	-	substrate: D-glucosamine 6-phosphate	Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glucoamine 6-phosphate	involved in formation of cell-wall precursor UDP-N-acetylglucosamine	Pseudomonas aeruginosa	D-glucosamine 1-phosphate	-	r
D-glucose 1-phosphate	50fold lower activity than phosphoglucosamine mutase activity	Pseudomonas aeruginosa	D-glucose 6-phosphate	-	?
D-Mannose 1-phosphate	5fold lower activity than phosphoglucosamine mutase activity	Pseudomonas aeruginosa	D-Mannose 6-phosphate	-	?

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Release 2023.1 (January 2023)