Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(E)-3-[4-(1-Imidazolylmethyl)phenyl]-2-propenoate | reversible | Sus scrofa | |
15-hydroperoxyeicosatetraenoic acid | - |
Sus scrofa | |
15-Hydroxy-11alpha,9alpha-(epoxymethano)-prosta-5,13-dienoic acid | reversible | Sus scrofa | |
15-Hydroxy-9alpha,11alpha-peroxidoprosta-5,13-dienoic acid | irreversible inactivation during catalysis, protection by (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoate and 15-hydroxy-11alpha,9alpha-(epoxymethano)-prosta-5,13-dienoic acid | Sus scrofa | |
Cu2+ | 1 mM, complete inhibition | Sus scrofa | |
Zn2+ | 1 mM, 50% inhibition | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.012 | - |
15-hydroxy-9alpha,11alpha-peroxiprosta-5,13-dienoic acid | - |
Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
immunoaffinity purification | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.231 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
15-hydroxy-9alpha,11alpha-peroxiprosta-5,13-dienoic acid | - |
Sus scrofa | ? | - |
? | |
Prostaglandin H2 | i.e. PGH2 | Sus scrofa | thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid | the ratio of 12-hydroxy-5,8,10-heptadecatrienoic acid to thromboxane B2 varries from 1.6 to 2.1 depending on the reaction conditions | ? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | hemoprotein | Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1 | - |
Zn2+ | - |
Sus scrofa |