Literature summary for 5.3.99.4 extracted from

Ishii, M.; Numaguchi, Y.; Okumura, K.; Kubota, R.; Ma, X.; Murakami, R.; Naruse, K.; Murohara, T.
Mesenchymal stem cell-based gene therapy with prostacyclin synthase enhanced neovascularization in hindlimb ischemia (2009), Atherosclerosis, 206, 109-118.

Search for more literature for 5.3.99.4

Application

Application	Comment	Organism
medicine	sustained release of prostaglandin I2 enhances the proangiogenic function of mesenchymal stem cells and subsequent muscle cell regrowth in the ischemic tissue suggesting potential therapeutic benefits of cell-based gene therapy for critical limb ischemia	Rattus norvegicus

Cloned(Commentary)

Cloned (Comment)	Organism
GFP-tagged cDNA containing the full-length rat prostacyclin synthase gene is inserted into an adenoviral DNA construct for in vitro gene transfer to murine and human mesenchymal stem cells	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
52000	-	determined by SDS-PAGE and Western Blot analysis	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
Prostaglandin H2	Rattus norvegicus	-	Prostaglandin I2	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q62969	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Prostaglandin H2	-	Rattus norvegicus	Prostaglandin I2	-	?

Synonyms

Synonyms	Comment	Organism
prostacyclin synthase	-	Rattus norvegicus

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Release 2023.1 (January 2023)