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Literature summary for 5.3.99.4 extracted from
- Spectral evidence for the cytochrome P450 nature of prostacyclin synthetase (1981), Biochem. Pharmacol., 30, 2033-2036.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid | - |
Sus scrofa |  |
| tranylcypromine | - |
Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Sus scrofa | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| (5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate | prostaglandin endoperoxyde PGH2 prostacyclin PGI2 , a mechanism with the participation of a heme-thiolate protein is proposed | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aorta | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Prostaglandin H2 | - |
Sus scrofa | Prostaglandin I2 | prostaglandin I2 | ? | |
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Release 2023.1 (January 2023)
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