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Literature summary for 5.3.99.3 extracted from
- Role of microsomal prostaglandin E synthase 1 in the kidney (2007), J. Am. Soc. Nephrol., 18, 1466-1475.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | in mice with targeted disruption of isoform mPGES-1 gene, basal excretion of prostaglandin E2 in urine is decreased by 50%. In female enzyme-deficient mice, there is a reciprocal increase in basal excretion of other prostanoids. Urinary osmolalities are similar in wild-type and enzyme deficient animals at baseline and after 12 h of water deprivation, and there are no differences in blood pressure on control or high- or low-salt diet. Furesemide-associated diuresis is reduced in male enzyme-deficient animals | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Mus musculus | - |
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Release 2023.1 (January 2023)
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