Cloned (Comment) | Organism |
---|---|
for expression in Escherichia coli BL21DE3 cells | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
DELTA1-24_C65A L-PGDS | mutant, preserves a disulfide bond between Cys89 and Cys186 | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
20000 | - |
L-PGDS | Mus musculus |
21000 | - |
L-PGDS bound to biliverdin | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | Mus musculus | - |
Prostaglandin D2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | O09114 | - |
- |
Purification (Comment) | Organism |
---|---|
the DELTA1-24_C65A L-PGDS mutant is purified on a glutathione-Sepharose 4B column and incubated with thrombin to release the L-PGDS, the protein is further purified by gel filtration | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | - |
Mus musculus | Prostaglandin D2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-PGDS | - |
Mus musculus |
lipocalin-type PGD synthase | - |
Mus musculus |
lipocalin-type prostaglandin d synthase | - |
Mus musculus |
Prostaglandin-H2 D-isomerase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | lipocalin-type prostaglandin D synthase acts as both a PGD2 synthase and an extracellular transporter for small lipophilic molecules | Mus musculus |