Application | Comment | Organism |
---|---|---|
medicine | the enzyme is a therapeutic target for preventing and treating inappropriate neutrophil sequestration | Mus musculus |
medicine | the enzyme is a therapeutic target for preventing and treating inappropriate neutrophil sequestration | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Mus musculus | - |
- |
extracellular | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Mus musculus | - |
blood platelet | - |
Homo sapiens | - |
lymphocyte | - |
Mus musculus | - |
lymphocyte | - |
Homo sapiens | - |
monocyte | - |
Mus musculus | - |
monocyte | - |
Homo sapiens | - |
neutrophil | - |
Mus musculus | - |
neutrophil | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
PDI | - |
Mus musculus |
PDI | - |
Homo sapiens |
protein disulfide isomerase | - |
Mus musculus |
protein disulfide isomerase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | extracellular protein disulfide isomerase (PDI) regulates ligand-binding activity of alphaMbeta2 integrin and neutrophil recruitment during vascular inflammation. Neutrophil PDI is required for neutrophil adhesion and crawling during tumor necrosis factor-alpha-induced vascular inflammation in vivo | Mus musculus |
physiological function | extracellular protein disulfide isomerase (PDI) regulates ligand-binding activity of alphaMbeta2 integrin and neutrophil recruitment during vascular inflammation. Neutrophil PDI is required for neutrophil adhesion and crawling during tumor necrosis factor-alpha-induced vascular inflammation in vivo | Homo sapiens |