Application | Comment | Organism |
---|---|---|
diagnostics | the absence of PDIp expression in pancreatic adenocarcinoma may serve as an additional biomarker for pancreatic cancer | Mus musculus |
diagnostics | the absence of PDIp expression in pancreatic adenocarcinoma may serve as an additional biomarker for pancreatic cancer | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epididymis | low expression level of PDIp | Mus musculus | - |
ileum | PDIp is exclusively expressed in Paneth cells | Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | low expression level of PDIp | Mus musculus | - |
lung | - |
Mus musculus | - |
additional information | no activity of PDIp in pancreatic adenocarcinoma cells | Homo sapiens | - |
additional information | no or poor expression of PDIp in colon, cecum, and duodenum. PDIp shows a cell-type specific expression in various mouse tissues, in the digestive organs, such as the stomach and pancreas, very high levels of PDIp are selectively expressed in the digestive enzyme-secreting cells | Mus musculus | - |
pancreas | - |
Homo sapiens | - |
pancreas | pancreas-specific protein disulfide isomerase, PDIp, specific expression in pancreatic acinar cells, high expression level of PDIp | Mus musculus | - |
spleen | low expression level of PDIp | Mus musculus | - |
stomach | specific expression of PDIp in gastric chief cells, high expression level of PDIp | Mus musculus | - |
uterus | high expression level of PDIp | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
pancreas-specific protein disulfide isomerase | - |
Mus musculus |
pancreas-specific protein disulfide isomerase | - |
Homo sapiens |
PDIp | - |
Mus musculus |
PDIp | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | PDIp may function as a protein-folding catalyst for secretory digestive enzymes | Mus musculus |