Application | Comment | Organism |
---|---|---|
medicine | PDI is required in vivo for both fibrin generation and platelet thrombus formation | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bacitracin | infusion of blood vessels inhibits platelet thrombus formation and fibrin generation | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | PDI is required in vivo for both fibrin generation and platelet thrombus formation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood vessel | time-dependent decrease in in PDI expression in thrombi following injury. Infusion of monoclonal antibodies against PDI into the circulation of mice lacking the G protein-coupled platelet receptor Par4 prior to vessel wall injury inhibits fibrin generation | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PDI is required in vivo for both fibrin generation and platelet thrombus formation | Mus musculus | ? | - |
? |