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Literature summary for 5.3.4.1 extracted from
- Cloning, characterization and regulation of a protein disulfide isomerase from the fission yeast Schizosaccharomyces pombe (2006), Mol. Biol. Rep., 33, 187-196.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | oxidaive stress by H2O2, and glucose deprivation or nitrogen starvation induce PDI enzyme expression | Schizosaccharomyces pombe |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene PDI, DNA and amino acid sequence determination and analysis, restriction mapping, expression in Escherichia coli strain MV1184 | Schizosaccharomyces pombe |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 39490 | - |
x * 39490, sequece calculation | Schizosaccharomyces pombe |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Schizosaccharomyces pombe | PDI is involved in the cellular growth and response to nutritional and oxidative stress, regulation, overview | ? | - |
? |  |
| additional information | Schizosaccharomyces pombe 972 | PDI is involved in the cellular growth and response to nutritional and oxidative stress, regulation, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Schizosaccharomyces pombe | O13811 | precursor; strain KP1 | - |
| Schizosaccharomyces pombe 972 | O13811 | precursor; strain KP1 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| insulin | reduction of insulin disulfide bonds | Schizosaccharomyces pombe | ? | - |
? | |
| insulin | reduction of insulin disulfide bonds | Schizosaccharomyces pombe 972 | ? | - |
? | |
| additional information | PDI is involved in the cellular growth and response to nutritional and oxidative stress, regulation, overview | Schizosaccharomyces pombe | ? | - |
? | |
| additional information | PDI is involved in the cellular growth and response to nutritional and oxidative stress, regulation, overview | Schizosaccharomyces pombe 972 | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 39490, sequece calculation | Schizosaccharomyces pombe |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDI | - |
Schizosaccharomyces pombe |
| protein disulfide isomerase | - |
Schizosaccharomyces pombe |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Schizosaccharomyces pombe |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| GSH | - |
Schizosaccharomyces pombe | |
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