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Literature summary for 5.3.3.12 extracted from

  • Ishimoto, K.; Iwata, T.; Taniguchi, H.; Mizusawa, N.; Tanaka, E.; Yoshimoto, K.
    D-dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytes (2012), Cytokine, 60, 772-777.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-dopachrome Homo sapiens
-
5,6-dihydroxyindole-2-carboxylate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
preadipocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-dopachrome
-
Homo sapiens 5,6-dihydroxyindole-2-carboxylate
-
?
L-dopachrome methyl ester
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
Macrophage migration inhibitory factor
-
Homo sapiens
MIF
-
Homo sapiens

General Information

General Information Comment Organism
physiological function mRNA expression matrix-metalloproteinase (MMP)-1 and MMP-3 are induced by the enzyme in SGB preadipocyte cell line Homo sapiens