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Literature summary for 5.3.1.9 extracted from

  • Fu, M.; Li, L.; Albrecht, T.; Johnson, J.D.; Kojic, L.D.; Nabi, I.R.
    Autocrine motility factor/phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release (2011), Cell Death Differ., 18, 1057-1070.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glucose 6-phosphate Chlorocebus sabaeus
-
D-fructose 6-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Chlorocebus sabaeus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
COS-7 cell
-
Chlorocebus sabaeus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose 6-phosphate
-
Chlorocebus sabaeus D-fructose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
AMF/PGI
-
Chlorocebus sabaeus
autocrine motility factor/phosphoglucose isomerase
-
Chlorocebus sabaeus

General Information

General Information Comment Organism
physiological function autocrine motility factor/phosphoglucose isomerase (AMF/PGI) regulates endoplasmic reticulm (ER) stress and cell death through control of ER calcium release. AMF/PGI also protects against thapsigargin- and tunicamycin-induced ER stress and apoptosis and suppresses cytosolic Ca2+ homeostasis Chlorocebus sabaeus