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Literature summary for 5.3.1.8 extracted from
- Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities (2008), Appl. Microbiol. Biotechnol., 80, 1015-1022.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | order of activation Mg2+ > Ca2+ > Mn2+ > Co2+ > Ni2+ | Burkholderia cenocepacia |  |
| Co2+ | order of activation Mg2+ > Ca2+ > Mn2+ > Co2+ > Ni2+ | Burkholderia cenocepacia | |
| Mg2+ | order of activation Mg2+ > Ca2+ > Mn2+ > Co2+ > Ni2+ | Burkholderia cenocepacia | |
| Mn2+ | Mg2+ > Ca2+ > Mn2+ > Co2+ > Ni2+ | Burkholderia cenocepacia | |
| Ni2+ | order of activation Mg2+ > Ca2+ > Mn2+ > Co2+ > Ni2+ | Burkholderia cenocepacia | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Burkholderia cenocepacia |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | inhibitory to both phosphomannose isomerase and guanosine diphosphate-D-mannose diphosphorylase activities | Burkholderia cenocepacia | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 12.4 | - |
D-mannose 6-phosphate | 30°C, pH 7.6 | Burkholderia cenocepacia | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55716 | - |
x * 55716, calculated, x * 56000, SDS-PAGE | Burkholderia cenocepacia |
| 56000 | - |
x * 55716, calculated, x * 56000, SDS-PAGE | Burkholderia cenocepacia |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Burkholderia cenocepacia | - |
bifunctional enzyme with phosphomannose isomerase and guanosine diphosphate-D-mannose diphosphorylase activities | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-Mannose 6-phosphate | - |
Burkholderia cenocepacia | D-Fructose 6-phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 55716, calculated, x * 56000, SDS-PAGE | Burkholderia cenocepacia |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BceAJ | - |
Burkholderia cenocepacia |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Burkholderia cenocepacia | calculated | - |
5.9 |
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Release 2023.1 (January 2023)
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