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Literature summary for 5.3.1.28 extracted from
- Identification of potential Leptospira phosphoheptose isomerase inhibitors through virtual high-throughput screening (2010), Genomics Proteomics Bioinformatics, 8, 246-255.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | Glu64, His181, Thr169, Thr122 and His60 are critical for enzyme activity | Leptospira interrogans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leptospira interrogans | Q72RC1 | serovars Lai and Copenhageni | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-sedoheptulose 7-phosphate | - |
Leptospira interrogans | D-glycero-D-manno-heptose 7-phosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GmhA | - |
Leptospira interrogans |
| phosphoheptose isomerase | - |
Leptospira interrogans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | phosphoheptose isomerase of Leptospira is vital for lipopolysaccharide biosynthesis | Leptospira interrogans |
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Release 2023.1 (January 2023)
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