Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Francisella tularensis |
expressed in Escherichia coli BL21(DE3) cells | Francisella tularensis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R,3R)-2,3-dihydroxy-4-(hydroxyamino)-4-oxobutyl phosphate | - |
Francisella tularensis | |
(2R,3R)-4-amino-2,3-dihydroxy-4-oxobutyl phosphate | - |
Francisella tularensis | |
(2S,3R)-2,3-bis(acetyloxy)-4-(hydroxyamino)-4-oxobutyl phosphate | - |
Francisella tularensis | |
oxido(dioxo)[(2R,3R)-N,2,3-trihydroxy-4-(hydroxy-kO)butanamidato]phosphate(2-) | - |
Francisella tularensis | |
[(2R,3R)-1-(hydroxy-kO)-4-(hydroxyamino)-4-oxobutane-2,3-diyl diacetatato](oxido)dioxophosphate(2-) | - |
Francisella tularensis | |
[(2R,3R)-2,3-dihydroxy-4-(hydroxy-kO)butanamidato](oxido)dioxophosphate(2-) | - |
Francisella tularensis | |
[(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl phosphate | - |
Francisella tularensis | |
[(4R,5R)-N-hydroxy-5-[(hydroxy-kO)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxamidato](oxido)dioxophosphate(2-) | - |
Francisella tularensis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.38 | - |
D-arabinose 5-phosphate | at 37°C, pH not specified in the publication | Francisella tularensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Arabinose 5-phosphate | Francisella tularensis | - |
D-Ribulose 5-phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Francisella tularensis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Francisella tularensis |
metal-affinity column chromatography | Francisella tularensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Arabinose 5-phosphate | - |
Francisella tularensis | D-Ribulose 5-phosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
A5PI | - |
Francisella tularensis |
D-Arabinose 5-phosphate isomerase | - |
Francisella tularensis |
KdsD | - |
Francisella tularensis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
141 | - |
D-arabinose 5-phosphate | at 37°C, pH not specified in the publication | Francisella tularensis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.007 | - |
[(2R,3R)-1-(hydroxy-kO)-4-(hydroxyamino)-4-oxobutane-2,3-diyl diacetatato](oxido)dioxophosphate(2-) | at 37°C, pH not specified in the publication | Francisella tularensis | |
0.01 | - |
[(2R,3R)-2,3-dihydroxy-4-(hydroxy-kO)butanamidato](oxido)dioxophosphate(2-) | at 37°C, pH not specified in the publication | Francisella tularensis | |
0.035 | - |
oxido(dioxo)[(2R,3R)-N,2,3-trihydroxy-4-(hydroxy-kO)butanamidato]phosphate(2-) | at 37°C, pH not specified in the publication | Francisella tularensis | |
3 | - |
[(4R,5R)-N-hydroxy-5-[(hydroxy-kO)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxamidato](oxido)dioxophosphate(2-) | at 37°C, pH not specified in the publication | Francisella tularensis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.007 | - |
pH and temperature not specified in the publication | Francisella tularensis | (2S,3R)-2,3-bis(acetyloxy)-4-(hydroxyamino)-4-oxobutyl phosphate | |
0.01 | - |
pH and temperature not specified in the publication | Francisella tularensis | (2R,3R)-4-amino-2,3-dihydroxy-4-oxobutyl phosphate | |
0.035 | - |
pH and temperature not specified in the publication | Francisella tularensis | (2R,3R)-2,3-dihydroxy-4-(hydroxyamino)-4-oxobutyl phosphate | |
3 | - |
pH and temperature not specified in the publication | Francisella tularensis | [(4R,5R)-5-(hydroxycarbamoyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl phosphate |