Protein Variants | Comment | Organism |
---|---|---|
additional information | depletion of Pin1 from HeLa cells causes a cytokinesis defect, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | in mitotic cells, Pin1 is located in the midbody ring | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | Pin1 enhances Plk1-mediated phosphorylation of the centrosome protein Cep55, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
HEK-293T cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Pin1 enhances Plk1-mediated phosphorylation of the centrosome protein Cep55, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
peptidyl-prolyl isomerase | - |
Homo sapiens |
Pin1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | Pin1 is deregulated in many tumors | Homo sapiens |
physiological function | the Pin1 is located in the midbody ring in HeLa cells and regulates cell cycle progression and cytokinesis through centrosome protein Cep55, which is an essential component of the midbody ring | Homo sapiens |