Cloned (Comment) | Organism |
---|---|
expression in 293-T cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C113A | mutation in isomerase domain, catalytically inert. Mutation diminishes binding to brain-specifc protein BNIP-H | Homo sapiens |
S16A | mutation in WW domain. Mutation diminishes binding to brain-specifc protein BNIP-H | Homo sapiens |
S16E | mutation in WW domain. Mutation diminishes binding to brain-specifc protein BNIP-H | Homo sapiens |
W34A | mutation in WW domain. Mutation diminishes binding to brain-specifc protein BNIP-H | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
More | isoform Pin1 interacts with brain-specifc protein BNIP-H after nerve growth factor stimulation. Both proteins co-localize in the neurites and cytosol of differentiating pheochromocytoma PC12 cells and the embryonic carcinoma P19 cells. Expression of Pin1 disrupts the BNIP-H/glutaminase complex formation in PC-12 cells under nerve growth factor-stimulation | Homo sapiens |