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Literature summary for 5.1.99.4 extracted from

  • Ouyang, B.; Leung, Y.K.; Wang, V.; Chung, E.; Levin, L.; Bracken, B.; Cheng, L.; Ho, S.M.
    alpha-Methylacyl-CoA racemase spliced variants and their expression in normal and malignant prostate tissues (2011), Urology, 77, 2491-2497.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.1.99.4

Application

Application Comment Organism
medicine AMACR is used as a diagnostic biomarker for prostate cancer and is a standard biomarker for needle biopsy specimens with ambiguous lesions Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UHK6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
NPrEC cell
-
 Homo sapiens
-
PC-3 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
alpha-methylacyl-CoA racemase
-
 Homo sapiens
AMACR
-
 Homo sapiens
P504S
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens transcript levels of most AMACR splice variants are significantly upregulated in prostate cancer compared with its adjacent normal counterparts (in the order: IA>> IAd = IIA>> IIAs> IAs), while splice variant IB is the most abundant form of B variant and expression of splice variant IIB is negligible up