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Literature summary for 5.1.99.4 extracted from

  • Kaic, G.; Tomasovic-Loncaric, C.
    alpha-methylacyl-CoA racemase (AMACR) in fine-needle aspiration specimens of prostate lesions (2009), Diagn. Cytopathol., 37, 803-808.
    View publication on PubMed
Search for more literature for 5.1.99.4

Application

Application Comment Organism
diagnostics the elevated expression of the P504S gene and its enzyme product can serve as a molecular marker for prostate cancer Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-
peroxisome
-
 Homo sapiens 5777
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gall bladder
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
lung
-
 Homo sapiens
-
prostate gland from patients with prostate carcinoma, atypia and benign hyperplasia Homo sapiens
-
salivary gland
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
alpha-methylacyl-CoA racemase
-
 Homo sapiens
AMACR
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens patients with benign prostate hyperplasia have negative expression of AMACR down
Homo sapiens in addition to the over-expression in prostate carcinoma, enzyme is also over-expressed in a number of adenocarcinomas, notably colorectal carcinoma as well as in hepatocellular and renal cell carcinoma up

General Information

General Information Comment Organism
physiological function enzyme is involved in the beta-oxidation of branched-chain fatty acids Homo sapiens