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Literature summary for 5.1.99.4 extracted from

  • Olgac, S.; Hutchinson, B.; Tickoo, S.K.; Reuter, V.E.
    alpha-Methylacyl-CoA racemase as a marker in the differential diagnosis of metanephric adenoma (2006), Mod. Pathol., 19, 218-224.
    View publication on PubMed

Application

Application Comment Organism
diagnostics the enzyme can be used as a marker in the differential diagnosis of metanephric adenoma and as a molecular marker for prostate carcinoma Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-
peroxisome
-
Homo sapiens 5777
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
Homo sapiens
-
colorectal cancer cell
-
Homo sapiens
-
metanephric adenoma cell from a renal neoplasm Homo sapiens
-
additional information immunohistochemic analysis, the enzyme is overexpressed in cancer tissue, such as breast, colorectal and ovarian cancers, no expression in epithelial type Wilms’ tumor Homo sapiens
-
ovarian cancer cell
-
Homo sapiens
-
papillary renal cell carcinoma cell
-
Homo sapiens
-
prostate carcinoma cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme catalyzes the racemization of alpha-methyl, branched carboxylic coenzyme A thioesters Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
alpha-methylacyl-CoA racemase
-
Homo sapiens
AMACR
-
Homo sapiens