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Literature summary for 5.1.3.8 extracted from
- The sialic acids. V. N-Acyl-D-glucosamine 2-epimerase (1965), J. Biol. Chem., 240, 1531-1536.
General Stability
| General Stability | Organism |
|---|---|
| not stable to freezing and thawing | Sus scrofa |
| stable to dialysis | Sus scrofa |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | inhibition can be overcome by Mg2+ | Sus scrofa |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
hog | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | cortex | Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 5.3 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-Acyl-D-glucosamine | r | Sus scrofa | N-Acyl-D-mannosamine | - |
? | |
| N-Acyl-D-glucosamine | also catalyzes epimerization of the corresponding N-glycolyl derivatives | Sus scrofa | N-Acyl-D-mannosamine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8 | - |
Sus scrofa |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.3 | 8.3 | 6.3: about 50% of maximal activity, 8.3: about 80% of maximal activity | Sus scrofa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | absolute requirement for ATP, but no conversion to ADP or AMP | Sus scrofa | |
| dATP | - |
Sus scrofa | |
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Release 2023.1 (January 2023)
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