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Literature summary for 5.1.3.29 extracted from

  • Park, D.; Ryu, K.S.; Choi, D.; Kwak, J.; Park, C.
    Characterization and role of fucose mutarotase in mammalian cells (2007), Glycobiology, 17, 955-962.
    View publication on PubMed
Search for more literature for 5.1.3.29

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells Mus musculus
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-L-fucopyranose Mus musculus the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway beta-L-fucopyranose
-
 r
alpha-L-fucopyranose Homo sapiens the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway beta-L-fucopyranose
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens A2VDF0
-
-
Mus musculus Q8R2K1
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-
liver
-
 Mus musculus
-
muscle marginal expression Mus musculus
-
pancreas
-
 Mus musculus
-
small intestine
-
 Mus musculus
-
testis marginal expression Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-L-fucopyranose the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway Mus musculus beta-L-fucopyranose
-
 r
alpha-L-fucopyranose the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway Homo sapiens beta-L-fucopyranose
-
 r
alpha-L-fucopyranose an exchange rate of alpha-to-beta conversion of L-fucose in the absence of FucU is extremely slow Mus musculus beta-L-fucopyranose
-
 r

Subunits

Subunits Comment Organism
More mainly homodimer, but exists also as homotetramer, homooctamer, and homodecamer. The homodimeric form seems to be catalytically inactive Mus musculus

Synonyms

Synonyms Comment Organism
FucU
-
 Mus musculus
FucU
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway Mus musculus
physiological function the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway Homo sapiens